Targeting toll-like receptor 9 with CpG oligodeoxynucleotides enhances anti-tumor responses of peripheral blood mononuclear cells from human lung cancer patients.

Targeting toll-like receptor 9 with CpG oligodeoxynucleotides enhances anti-tumor responses of peripheral blood mononuclear cells from human lung cancer patients.

Source :

• Cancer investigation [ 1532-4192 ] ; 2008.

Descripteurs français

• KwdFr :
  • Adjuvants immunologiques (pharmacologie), Agranulocytes (), Agranulocytes (immunologie), Agranulocytes (transplantation), Animaux, Antinéoplasiques (pharmacologie), Cellules cancéreuses en culture, Cellules cultivées, Chloroquine (pharmacologie), Cytotoxicité immunologique (), Facteur de nécrose tumorale alpha (métabolisme), Facteurs temps, Humains, Immunothérapie (), Immunothérapie adoptive, Interféron alpha (métabolisme), Interleukine-12 (métabolisme), Lymphocytes T CD8+ (), Lymphocytes T CD8+ (immunologie), Oligodésoxyribonucléotides (pharmacologie), Prolifération cellulaire (), Relation dose-effet des médicaments, Récepteur-9 de type Toll-like (métabolisme), Souris, Souris de lignée BALB C, Souris nude, Tumeurs du poumon (), Tumeurs du poumon (immunologie).
• MESH :
  • immunologie : Agranulocytes, Lymphocytes T CD8+, Tumeurs du poumon.
  • métabolisme : Facteur de nécrose tumorale alpha, Interféron alpha, Interleukine-12, Récepteur-9 de type Toll-like.
  • pharmacologie : Adjuvants immunologiques, Antinéoplasiques, Chloroquine, Oligodésoxyribonucléotides.
  • Agranulocytes, Animaux, Cellules cancéreuses en culture, Cellules cultivées, Cytotoxicité immunologique, Facteurs temps, Humains, Immunothérapie, Immunothérapie adoptive, Lymphocytes T CD8+, Prolifération cellulaire, Relation dose-effet des médicaments, Souris, Souris de lignée BALB C, Souris nude, Tumeurs du poumon.

English descriptors

• KwdEn :
  • Adjuvants, Immunologic (pharmacology), Animals, Antineoplastic Agents (pharmacology), CD8-Positive T-Lymphocytes (drug effects), CD8-Positive T-Lymphocytes (immunology), Cell Proliferation (drug effects), Cells, Cultured, Chloroquine (pharmacology), Cytotoxicity, Immunologic (drug effects), Dose-Response Relationship, Drug, Humans, Immunotherapy (methods), Immunotherapy, Adoptive, Interferon-alpha (metabolism), Interleukin-12 (metabolism), Leukocytes, Mononuclear (drug effects), Leukocytes, Mononuclear (immunology), Leukocytes, Mononuclear (transplantation), Lung Neoplasms (immunology), Lung Neoplasms (therapy), Mice, Mice, Inbred BALB C, Mice, Nude, Oligodeoxyribonucleotides (pharmacology), Time Factors, Toll-Like Receptor 9 (metabolism), Tumor Cells, Cultured, Tumor Necrosis Factor-alpha (metabolism).
• MESH :
  • chemical , metabolism : Interferon-alpha, Interleukin-12, Toll-Like Receptor 9, Tumor Necrosis Factor-alpha.
  • chemical , pharmacology : Adjuvants, Immunologic, Antineoplastic Agents, Chloroquine, Oligodeoxyribonucleotides.
  • drug effects : CD8-Positive T-Lymphocytes, Cell Proliferation, Cytotoxicity, Immunologic, Leukocytes, Mononuclear.
  • immunology : CD8-Positive T-Lymphocytes, Leukocytes, Mononuclear, Lung Neoplasms.
  • methods : Immunotherapy.
  • therapy : Lung Neoplasms.
  • transplantation : Leukocytes, Mononuclear.
  • Animals, Cells, Cultured, Dose-Response Relationship, Drug, Humans, Immunotherapy, Adoptive, Mice, Mice, Inbred BALB C, Mice, Nude, Time Factors, Tumor Cells, Cultured.

Abstract

Affiliations:

• République populaire de Chine

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